WS03. 7 Coexistence of prey and predator bacteria in cystic fibrosis lung microbiota
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01/06/2017Estado
info:eu-repo/semantics/publishedVersionMetadatos
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Los análisis basados ​​en el ADN de muestras de vías respiratorias con FQ han desafiado las ideas sobre la etiología de las infecciones por FQ. Dos hallazgos notables son: (1) En la enfermedad pulmonar con FQ temprana, el ADN microbiano en las muestras generalmente deriva de diversas colecciones de microbios no considerados patógenos convencionales de la FQ. (2) En la enfermedad establecida (cuando dominan los patógenos convencionales de la FQ) los patógenos no convencionales son aún identificado, aunque en menor cantidad. Estos hallazgos son complicados porque las muestras de las vías respiratorias transitan por la orofaringe donde los patógenos no convencionales son muy abundantes. Además, los dispositivos de recolección (por ejemplo, broncoscopios) y los reactivos de análisis albergan ADN microbiano. DNA-based analyses of CF airway samples have challenged ideas about the etiology of CF infections. Two notable findings are:(1) In early CF lung disease, the microbial DNA in samples typically derives from diverse collections of microbes not considered conventional CF pathogens.(2) In established disease (when conventional CF pathogens dominate) non-conventional pathogens are still identified, although in lesser quantities. These findings are complicated because airway samples transit through the oropharynx where non-conventional pathogens are highly abundant. In addition, collection devices (eg bronchoscopes) and analysis reagents harbor microbial DNA
WS03. 7 Coexistence of prey and predator bacteria in cystic fibrosis lung microbiota
Tipo de Actividad
Artículos en revistasISSN
1569-1993Palabras Clave
DNA-based analyses of CF airway samples have challenged ideas about the etiology of CF infections. Two notable findings are:(1) In early CF lung disease, the microbial DNA in samples typically derives from diverse collections of microbes not considered conventional CF pathogens.(2) In established disease (when conventional CF pathogens dominate) non-conventional pathogens are still identified, although in lesser quantities. These findings are complicated because airway samples transit through the oropharynx where non-conventional pathogens are highly abundant. In addition, collection devices (eg bronchoscopes) and analysis reagents harbor microbial DNADNA-based analyses of CF airway samples have challenged ideas about the etiology of CF infections. Two notable findings are:(1) In early CF lung disease, the microbial DNA in samples typically derives from diverse collections of microbes not considered conventional CF pathogens.(2) In established disease (when conventional CF pathogens dominate) non-conventional pathogens are still identified, although in lesser quantities. These findings are complicated because airway samples transit through the oropharynx where non-conventional pathogens are highly abundant. In addition, collection devices (eg bronchoscopes) and analysis reagents harbor microbial DNA