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Effects of vancomycin, cefazolin and test conditions on the wear behavior of bone cement

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IIT-13-044A.pdf (2.183Mb)
Fecha
2014-01-01
Autor
Sanz Ruiz, Pablo
Paz Jiménez, Eva
Abenojar Buendía, Juana
del Real Romero, Juan Carlos
Vaquero Martín, Javier
Forriol Campos, Francisco Luis
Estado
info:eu-repo/semantics/publishedVersion
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Resumen
 
 
Antibiotic cement has been recommended in the treatment of prosthetic infections. The purpose of this study was to investigate the mechanical behavioral changes in cement loaded with two antibiotics, vancomycin and cefazolin, in dry and liquid medium. Six groups and four study conditions were established according to the doses of antibiotic used and the ageing (immersion in phosphate buffered saline) of the samples. Properties evaluated were friction coefficient and wear. Samples in dry medium showed higher wears than in liquid. Antibiotic selection did not influence wear properties tested in dry conditions, however, in liquid medium, there were higher frictional coefficients and wear for cefazolin loaded cement after one week and for vancomycin and cefazolin after one month. The results suggest that antibiotic cements behave differently in liquid and that the molecular characteristics of antibiotics are essential for determining this influence.
 
URI
https:doi.org10.1016j.arth.2013.04.008
Effects of vancomycin, cefazolin and test conditions on the wear behavior of bone cement
Tipo de Actividad
Artículos en revistas
ISSN
0883-5403
Materias/ categorías / ODS
Instituto de Investigación Tecnológica (IIT)
Palabras Clave

polymethylmethacrylate (PMMA), bone cement, friction, arthroplasty infection, antibiotic-loaded cement
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Repositorio de la Universidad Pontificia Comillas copyright © 2015  Desarrollado con DSpace Software
Contacto | Sugerencias