Retrospective Cohort Noninferiority Analysis of Barrier Cream in Preventing Pressure Injuries
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Date
2021-05-01Author
Estado
info:eu-repo/semantics/publishedVersionMetadata
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. OBJECTIVE
To assess the effectiveness of a dimethicone- and zinc-based barrier cream compared with hyperoxygenated fatty acids in preventing pressure injuries (PIs) in patients at high or very high risk.
METHODS
Researchers conducted a retrospective noninferiority study in an inpatient acute care hospital in Spain that included hospitalized patients in nonsurgical departments with impaired mobility.
RESULTS
The study authors reviewed 522 patients in a control group (hyperoxygenated fatty acids) and an experimental group (barrier cream) over a period of 7 days. The incidence of PI was 31% in the control group and 31.1% in the experimental group. The hazard ratio for developing PI was 0.84 (confidence interval, 0.61-1.17; P = .32) in the experimental group compared with the control group, meeting the criteria for noninferiority. The Kaplan-Meier estimator indicated no statistically significant difference between groups (log-rank = 0.654).
CONCLUSIONS
Dimethicone- and zinc-based barrier cream was not inferior to hyperoxygenated fatty acids in preventing PIs in hospitalized patients at high or very high risk of developing them during their hospital stay.
Retrospective Cohort Noninferiority Analysis of Barrier Cream in Preventing Pressure Injuries
Tipo de Actividad
Artículos en revistasISSN
1538-8654Palabras Clave
..acute care, barrier cream, hyperoxygenated fatty acids, pressure injury, prevention, wound care, zinc