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Chronic respiratory diseases as a risk factor for Herpes Zoster infection
dc.contributor.author | Morena Valles, Diego Diego | es-ES |
dc.contributor.author | Lumbreras Sancho, Sara | es-ES |
dc.contributor.author | Rodriguez Gonzalez-Moro, José Miguel | es-ES |
dc.contributor.author | Campos Pérez, Carolina | es-ES |
dc.contributor.author | Castillo García, María | es-ES |
dc.contributor.author | Benavent Núñez, María | es-ES |
dc.contributor.author | Izquierdo Alonso, José L | es-ES |
dc.date.accessioned | 2024-02-23T13:18:05Z | |
dc.date.available | 2024-02-23T13:18:05Z | |
dc.date.issued | 2023-12-01 | es_ES |
dc.identifier.issn | 0300-2896 | es_ES |
dc.identifier.uri | https:doi.org10.1016j.arbres.2023.08.010 | es_ES |
dc.description | Artículos en revistas | es_ES |
dc.description.abstract | es-ES | |
dc.description.abstract | Introduction Herpes zoster (HZ) is a condition that results from the reactivation of the varicella zoster virus (VZV). Several diseases have been reported to increase the risk of developing HZ and postherpetic neuralgia (PHN). The objective of this study is to analyze the prevalence and risk factors for HZ and PHN in the most frequent chronic respiratory diseases, which are chronic obstructive pulmonary disease (COPD), asthma, lung cancer and obstructive sleep apnea (OSA). Methods We conducted an observational, retrospective, non-interventional study between January 2012 and December 2020 based on data from the Castilla-La Mancha Regional Health System in Spain. We used the Savana Manager 3.0 artificial intelligence-enabled system to collect information from electronic medical records. Results 31 765 subjects presented a diagnosis of HZ. Mean age was 64.5 years (95CI 64.3–64.7), and 58.2 were women. The prevalence of HZ showed an increasing trend in patients over the age of 50. A risk analysis adjusted for sex and comorbidities in COPD, asthma, lung cancer and OSA presented a higher risk of developing HZ in the first three (OR 1.16 [95CI 1.13–1.19], 1.67 [1.63–1.71], 1.68 [1.60–1.76], respectively), which further increased in all three when associated with comorbidities. Regarding postherpetic neuralgia, an increased risk was only observed related to COPD and lung cancer (OR 1.24 [95CI 1.23–1.25], 1.14 [1.13–1.16], respectively), further increasing when associated with comorbidities. Conclusions In a standard clinical practice setting, the most prevalent respiratory diseases (asthma, COPD and lung cancer) are related to a higher risk of HZ and PHN. These data are fundamental to assess the potential impact of vaccination in this population. | en-GB |
dc.format.mimetype | application/pdf | es_ES |
dc.language.iso | en-GB | es_ES |
dc.rights | es_ES | |
dc.rights.uri | es_ES | |
dc.source | Revista: Archivos de Bronconeumologia, Periodo: 1, Volumen: online, Número: 12, Página inicial: 797, Página final: 804 | es_ES |
dc.subject.other | Instituto de Investigación Tecnológica (IIT) | es_ES |
dc.title | Chronic respiratory diseases as a risk factor for Herpes Zoster infection | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.description.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | es_ES |
dc.keywords | es-ES | |
dc.keywords | Asthma; Chronic obstructive pulmonary disease; Herpes zoster; Lung cancer; Postherpetic neuralgia; Obstructive sleep apnea; Artificial intelligence | en-GB |
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