Modelling the gut microbiota ecosystem

Abstract

The application of the recent molecular techniques based on massive nucleotide sequencing for the study of the composition of the intestinal microbiota has allowed us to discover an exciting and completely unknown ecosystem. In addition, it has been demonstrated that alterations in their composition or functionality are linked to numerous gastrointestinal and systemic diseases. In recent years, numerous studies have shown the influence of gut microbiota on human health and, consequently, numerous research lines have been established to optimize health influencing this ecosystem. However, the regulation rules of this bionetwork have not yet been deciphered, and this knowledge is crucial to be able to modulate the ecosystem. The modulation of the microbiota needs not only physician approximations, but also biological, ecological, biochemical and physical. The microorganisms maintain a close relationship with the host and this complicates the restoration of the ecosystem.

The application of the recent molecular techniques based on massive nucleotide sequencing for the study of the composition of the intestinal microbiota has allowed us to discover an exciting and completely unknown ecosystem. In addition, it has been demonstrated that alterations in their composition or functionality are linked to numerous gastrointestinal and systemic diseases. In recent years, numerous studies have shown the influence of gut microbiota on human health and, consequently, numerous research lines have been established to optimize health influencing this ecosystem. However, the regulation rules of this bionetwork have not yet been deciphered, and this knowledge is crucial to be able to modulate the ecosystem. The modulation of the microbiota needs not only physician approximations, but also biological, ecological, biochemical and physical. The microorganisms maintain a close relationship with the host and this complicates the restoration of the ecosystem.